ENDOTHERMELASER ™ 1470 is a diode laser device used in endovascular laser ablation for the treatment of Primary varicose veins of the lower extremity. The device has been evaluated in a domestic multicenter clinical trial in terms of efficacy and safety for the treatment of varicose veins of the lower extremity.

Trade Name：LSO1470レーザー
Approval Number：22700BZX00311000
Marketing Approval Holder：MEDICO’S HIRATA INC.

Adopted 1470nm wavelength laser
　・Since 1470nm wavelength laser is highly absorbable to water, it will be well absorbed
　　into a venous wall when irradiated in the blood vessel. The laser absorbed is converted
　　to thermal energy to denature collagen fibers and contract the venous wall.

Ringlight™ Fiber Probe
　・Ringlight™ Fiber Probe which irradiates laser circumferentially in 360 degrees cauterizes
　　a target vessel uniformly. Since irradiating energy is dispersed, chances for blood vessel
　　perforation are reduced and safer treatment can be expected. Physicians can select one
　　from 2 kinds of laser fibers according to sizes or anatomy of their cases. 　

Clinical Trial Results
　・ENDOTHERMELASER™1470 has been evaluated in efficacy and safety for the treatment of
　　varicose veins of the lower extremity in the domestic multicenter clinical trial.
　　　　・Achieved a 100%, total cutting off the bloodstream in 6 months (24weeks)
　　　　　post-operation.
　　　　・Showed a significant reduction in VFI values (evaluation values of venous
　　　　　blood regurgitation).
　　　　・Indicated no occurrence of serious adverse events.
　　　　（The Clinical Trial was conducted with a standard fiber of 1.8mm. )